Anti-Human/Mouse/Rat BCL10 Polyclonal Antibody

This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12537
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human BCL10
Specificity Ubiquitous.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot O95999
Concentration 0.4 mg/mL
Dilution WB 1:500-1:2000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names AI132454,B cell CLL/lymphoma 10,B cell lymphoma/leukemia10,B-cell CLL/lymphoma 10,B-cell leukemia/lymphoma 10,B-cell lymphoma/leukemia 10,Bcl 10,Bcl-10,Bcl10,BCL10,c E10,c-E10,C81403,CARD containing apoptotic signaling protein,CARD containing molecule enhancing NF kappa B,CARD containing molecule enhancing NF kB,CARD containing molecule enhancing NF-kB,CARD containing molecule enhancing NFkB,CARD containing proapoptotic protein,CARD like apoptotic protein,CARD-containing apoptotic signaling protein,CARD-containing molecule enhancing NF-kappa-B,CARD-containing proapoptotic protein,CARD-like apoptotic protein,CARMEN,Caspase recruiting domain containing protein,caspase-recruiting domain-containing protein,cCARMEN,cE 10,cE10,CED 3/ICH 1 prodomain homologous E10 like regulator,CED-3/ICH-1 prodomain homologous E10-like regulator,CED3/ICH1 prodomain homologous E10 like regulator,Cellular E10,Cellular homolog of vCARMEN,Cellular-E10,CIPER,CLAP,hCLAP,Mammalian CARD containing adapter molecule E10,Mammalian CARD-containing adapter molecule E10,mE 10,mE10,R-RCD1
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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