Anti-Human/Mouse/Rat ASAH2 Polyclonal Antibody

Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12605
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ASAH2
Specificity Primarily expressed in the intestine (PubMed:17334805). Ubiquitously expressed with higher levels in kidney, skeletal muscle and heart (PubMed:10781606). According to PubMed:17334805, ubiquitous expression attributed to ASAH2 may be actually that of the paralog ASAH2B.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q9NR71
Concentration 0.7 mg/mL
Dilution WB 1:200-1:1000, IHC 1:25-1:100
Formulation
Application WB,IHC,ELISA
Other Names Acylsphingosine deacylase 2,AI585898,ASAH2,ASAH2,BCDase,hCD,HNAC1,LCDase,MGC129777,mitochondrial ceramidase,N acylsphingosine amidohydrolase (non lysosomal ceramidase) 2,N acylsphingosine amidohydrolase 2,N CDase,N-acylsphingosine amidohydrolase 2,N-CDase,NCDase,Neutral ceramidase soluble form,Non lysosomal ceramidase,Non-lysosomal ceramidase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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