Anti-Human/Mouse/Rat ACVR1C Polyclonal Antibody

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12894
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ACVR1C
Specificity Present in pancreas, heart, colon, small intestine, ovary and the hippocampus, medulla oblongata and putamen of the brain. Isoform 1, isoform 2, isoform 3 and isoform 4 are all expressed in the placenta throughout pregnancy.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q8NER5
Concentration 0.2 mg/mL
Dilution IHC 1:15-1:50
Formulation
Application IHC,ELISA
Other Names Activin A receptor,type IC,Activin receptor like kinase 7,Activin receptor type 1C precursor,Activin receptor type IC,Activin receptor type-1C,Activin receptor-like kinase 7,ACTR IC,ACTR-IC,ACTRIC,ACV1C,Acvr1c,ACVRLK7,ALK 7,ALK-7,ALK7
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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