Anti-Human/Mouse/Rat Acetyl-p57kip2 (Lys278) Polyclonal Antibody

Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01432
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human p57 around the acetylation site of K278.
Specificity Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot P49918
Concentration 1mg/mL
Dilution WB 1:500-1:2000, ELISA 1:20000
Formulation
Application WB,ELISA
Other Names Beckwith Wiedemann syndrome,BWCR,BWS,CDKI,CDKN 1C,CDKN1C,CDN1C,Cyclin dependent kinase inhibitor 1C,Cyclin dependent kinase inhibitor p57,Cyclin-dependent kinase inhibitor 1C,Cyclin-dependent kinase inhibitor p57,KIP 2,KIP2,p57,p57 Kip 2,p57KIP2,WBS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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