Anti-Human/Mouse/Rat Acetyl-Nrf2 (Lys599) Polyclonal Antibody

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01448
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599.
Specificity Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle.
Isotype IgG
Reacitivity Human,Mouse,Rat
Clone
Uniprot Q16236
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-300, ELISA 1:10000
Formulation
Application WB,IHC-p,ELISA
Other Names erythroid derived 2,HEBP1,like 2,NF E2 related factor 2,NF-E2-related factor 2,NF2L2,NFE2 related factor 2,NFE2-related factor 2,Nfe2l2,Nrf 2,NRF2,Nuclear factor (erythroid derived 2) like 2,Nuclear factor,nuclear factor erythroid 2 like 2,Nuclear factor erythroid 2 related factor 2,Nuclear factor erythroid 2-related factor 2,Nuclear factor erythroid derived 2 like 2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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