Anti-Human/Mouse Phospho-FOXO4 (Ser197) Polyclonal Antibody

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01560
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human FoxO4 around the phosphorylation site of Ser197
Specificity Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P98177
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IHC-p,ELISA
Other Names AFX,AFX1,Afxh,ALL1-fused gene from X chromosome,Fork head domain transcription factor AFX1,Forkhead box O4,Forkhead box protein O4,FOXO 4,Foxo4,FOXO4,MGC117660,MGC120490,Mixed lineage leukemia,translocated to,7,MLLT7,Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog,Drosophila),translocated to,7,Myeloid/lymphoid or mixed lineage leukemia,translocated to,7,RGD1561201
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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