Anti-Human/Mouse PAEP Polyclonal Antibody

This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12051
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human PAEP
Specificity This protein is, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy (PubMed:3667877). Glycodelin-A is expressed in amniotic fluid, endometrium/decidua and maternal serum (at protein level) (PubMed:3194393). Glycodelin-F is expressed in follicular fluid, luteinized granulosa cells and the oviduct (at protein level) (PubMed:12672671). Glycodelin-S is expressed in seminal plasma and seminal vesicles (at protein level) (PubMed:9239694). Glycodelin-C is detected in cumulus cells (at protein level), but cumulus cells do not synthesize Glycodelin-C but take up and convert glycodelin-A and -F vis glycan remodeling (PubMed:17192260).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot P09466
Concentration 0.6 mg/mL
Dilution WB 1:500-1:2000, IHC 1:100-1:300
Formulation
Application WB,IHC,ELISA
Other Names Alpha uterine protein,gD,GdA,GdF,GdS,Glycodelin A,Glycodelin,Glycodelin F,Glycodelin S,MGC138509,MGC142288,PAEG,PAEP,PAEP,PEG,PEP,Placental protein 14,PP14,Pregnancy-associated endometrial alpha-2 globulin,Progestagen-associated endometrial protein,Progesterone-associated endometrial protein
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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