Anti-Human/Mouse P3H3 Polyclonal Antibody

The protein encoded by this gene belongs to the leprecan family of proteoglycans, which function as collagen prolyl hydroxylases that are required for proper collagen biosynthesis, folding and assembly. This protein, like other family members, is thought to reside in the endoplasmic reticulum. Epigenetic inactivation of this gene is associated with breast and other cancers, suggesting that it may function as a tumor suppressor.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11941
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human LEPREL2
Specificity Detected in fetal cartilage (at protein level) (PubMed:28115524). Weak expression in heart, lung, ovary and skeletal muscle (PubMed:8723724).
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8IVL6
Concentration 0.2 mg/mL
Dilution IHC 1:50-1:200
Formulation
Application IHC,ELISA
Other Names GRCB,P3H3,HSU47926
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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