Anti-Human/Mouse MSH4 Polyclonal Antibody

This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12464
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human MSH4
Specificity Testis and ovary specific.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O15457
Concentration 0.5 mg/mL
Dilution IHC 1:100-1:300
Formulation
Application IHC,ELISA
Other Names hMSH4,MSH 4,MSH4,MSH4,MutS homolog 4 (E. Coli),MutS homolog 4,MutS protein homolog 4
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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