Anti-Human/Mouse/Monkey Phospho-DOK2 (Tyr299) Polyclonal Antibody

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA01543
Size 100μl
Host Type Rabbit
Immunogen Synthesized peptide derived from human Dok-2 around the phosphorylation site of Tyr299
Specificity Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver.
Isotype IgG
Reacitivity Human,Mouse,Monkey
Clone
Uniprot O60496
Concentration 1mg/mL
Dilution WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
Formulation
Application WB,IF,ELISA
Other Names Docking protein 2 56kDa,Docking protein 2,DOK 2,DOK R,DOK2,DOK2,Downstream of tyrosine kinase 2,OTTHUMP00000161710,OTTHUMP00000224923,p56(dok 2),p56(dok-2),p56dok 2,p56DOK,p56dok2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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