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Anti-Human/Mouse IGF2BP3 Polyclonal Antibody

Categories: [ Antibodies][ Polyclonal Antibodies]
The protein encoded by this gene is primarily found in the nucleolus, where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains, which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7, and there are putative pseudogenes on other chromosomes.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12332
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human IGF2BP3
Specificity Expressed in fetal liver, fetal lung, fetal kidney, fetal thymus, fetal placenta, fetal follicles of ovary and gonocytes of testis, growing oocytes, spermatogonia and semen (at protein level). Expressed in cervix adenocarcinoma, in testicular, pancreatic and renal-cell carcinomas (at protein level). Expressed ubiquitously during fetal development at 8 and 14 weeks of gestation. Expressed in ovary, testis, brain, placenta, pancreatic cancer tissues and pancreatic cancer cell lines.
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot O00425
Concentration 0.1 mg/mL
Dilution WB 1:500-1:2000
Formulation
Application WB,ELISA
Other Names Cancer/testis antigen 98,CT98,DKFZp686F1078,hKOC,IF2B3,IGF II mRNA binding protein 3,IGF-II mRNA-binding protein 3,IGF2 mRNA binding protein 3,IGF2 mRNA-binding protein 3,IGF2BP3,IMP 3,IMP-3,Insulin like growth factor 2 mRNA binding protein 3,Insulin-like growth factor 2 mRNA-binding protein 3,KH domain containing protein overexpressed in cancer,KH domain-containing protein overexpressed in cancer,KOC 1,KOC1,VICKZ 3,VICKZ family member 3,VICKZ3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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