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Anti-Human/Mouse HSD17B10 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
HSD17B10 (3-hydroxyacyl-CoA dehydrogenase type-2) is a multifunctional mitochondrial enzyme that acts on a wide spectrum of substrates,including neuroactive steroids,alcohols,leucine,and fatty acids,with a preference for short-chain methyl-branched acyl-CoAs.It has 2 isoforms produced by alternative splicing.Defects in HSD17B10 are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD deficiency) and mental retardation syndromic X-linked type 10 (MRXS10).
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02291
Size 100μl
Host Type Mouse
Immunogen Fusion protein of ERAB
Specificity Expressed in normal tissues but is overexpressed in neurons affected in AD.
Isotype IgG1
Reacitivity Human,Mouse
Clone 9546
Uniprot Q99714
Concentration None
Dilution WB 1:1000-1:10000
Formulation
Application WB,ELISA
Other Names 17 beta hydroxysteroid dehydrogenase 10,17 beta hydroxysteroid dehydrogenase type 10,17-beta-HSD 10,17-beta-hydroxysteroid dehydrogenase 10,17b HSD10,3 hydroxy 2 methylbutyryl CoA dehydrogenase,3 hydroxyacyl CoA dehydrogenase type 2,3 hydroxyacyl CoA dehydrogenase type II,3-hydroxy-2-methylbutyryl-CoA dehydrogenase,3-hydroxyacyl-CoA dehydrogenase type II,3-hydroxyacyl-CoA dehydrogenase type-2,AB binding alcohol dehydrogenase,ABAD,Ads9,Amyloid beta binding polypeptide,Amyloid beta peptide binding alcohol dehydrogenase,Amyloid beta peptide binding protein,Amyloid beta peptide binding protein,CAMR,DUPXp11.22,Endoplasmic Reticulum Amyloid Binding Protein,Endoplasmic reticulum associated amyloid beta peptide binding protein,Endoplasmic reticulum-associated amyloid beta-peptide-binding protein,ER associated amyloid beta-binding protein,ERAB,HADH 2,HADH2,HCD 2,HCD2,HCD2,Hsd17b10,Hydroxyacyl CoA Dehydrogenase type II,Hydroxyacyl Coenzyme A dehydrogenase type II,Hydroxysteroid (17 beta) dehydrogenase 10,Mental retardation X linked syndromic 11,MHBD,Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase,Mitochondrial ribonuclease P protein 2,Mitochondrial RNase P protein 2,MRPP2,MRX17,SCHAD,SDR5C1,Short chain dehydrogenase/reductase family 5C member 1,Short chain L 3 hydroxyacyl CoA dehydrogenase type 2,Short chain type dehydrogenase/reductase XH98G2,Short-chain type dehydrogenase/reductase XH98G2,Type 10 17b HSD,Type 10 17beta hydroxysteroid dehydrogenase,Type II HADH,XH98G2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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