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Anti-Human/Mouse CXCR4 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
The chemokine receptor CXCR4,a 7-transmembrane protein on cell surface,acts with the CD4 protein to support HIV entry into cells. CXCR4 is highly expressed in brain and heart,white blood cells,vascular endothelial cells,and umbilical cord endothelial cells. Several CXCR4 isoforms have been identified with molecular weights of 47,50,62 and 98kDa. The 62-64kDa CXCR4 is predominantly ubiquitinated and is preferentially associated with CD4. This antibody recognizes the 62kd CXCR4.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01940
Size 100μl
Host Type Mouse
Immunogen Fusion protein of CXCR4
Specificity Expressed in numerous tissues, such as peripheral blood leukocytes, spleen, thymus, spinal cord, heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, cerebellum, cerebral cortex and medulla (in microglia as well as in astrocytes), brain microvascular, coronary artery and umbilical cord endothelial cells. Isoform 1 is predominant in all tissues tested.
Isotype IgM
Reacitivity Human,Mouse
Clone 226
Uniprot P61073
Concentration None
Dilution WB 1:500-1:5000
Formulation
Application WB,ELISA
Other Names C-X-C chemokine receptor type 4,CD184,CD184 antigen,Chemokine (C X C motif) receptor 4,Chemokine CXC Motif Receptor 4,CXC-R4,CXCR-4,CXCR4,CXCR4,D2S201E,FB22,Fusin,HM89,HSY3RR,LAP 3,LAP3,LCR1,LESTR,Leukocyte derived seven transmembrane domain receptor,Leukocyte-derived seven transmembrane domain receptor,Lipopolysaccharide associated protein 3,Neuropeptide Y receptor Y3,NPY3R,NPYR,NPYRL,NPYY3,NPYY3R,Probable G protein coupled receptor lcr1 homolog,SDF 1 receptor,SDF-1 receptor,SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR,Stromal cell derived factor 1 receptor,Stromal cell-derived factor 1 receptor,WHIM,WHIMS
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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