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Anti-Human/Mouse CK-15 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated,tissue specific,and varies according to cell-state. Type I keratins consist of acidic,low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral,high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18). Keratin 15 is a type I cytokeratin. It is found in some progenitor basal cells within complex epithelia.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01946
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Cytokeratin 15
Specificity Expressed in a discontinuous manner in the basal cell layer of adult skin epidermis, but continuously in the basal layer of fetal skin epidermis and nail. Also expressed in the outer root sheath above the hair bulb in hair follicle (at protein level). Expressed homogeneously in all cell layers of the esophagus and exocervix, but detected in the basal cell layer only of oral mucosa, skin and in the basal plus the next two layers of the suprabasal epithelium of the palate.
Isotype IgG1
Reacitivity Human,Mouse
Clone 437
Uniprot P19012
Concentration None
Dilution WB 1:500-1:5000, IHC 1:100-1:1000, IF 1:10-1:100
Formulation
Application WB,IHC,IF,ELISA
Other Names AI528832,CK 15,CK-15,CK15,Cytokeratin-15,Cytokeratin15,K15,K1C15,K1CO,Ka15,Keratin 15,Keratin 15 basic,Keratin 15 beta,Keratin,Keratin complex 1 acidic gene 15,Keratin type I cytoskeletal 15,Keratin-15,Keratin15,KRT 15,Krt1-15,KRT15,KRTB,KRTL15,Type I cytoskeletal 15,Type I keratin Ka15
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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