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Anti-Human/Mouse CASP8 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Caspase 8,also named as MCH5,MACH,FLICE,and CAP4,belongs to the peptidase C14A family. It may participate in the GZMB apoptotic pathways and functions as an upstream regulator in a-bisabolol-induced apoptosis. Caspase 8 catalyzes an essential intermediate step in the ubiquitination and proteasome-mediated degradation of IRF3. It may control diabetic embryopathy-associated apoptosis via Caspase 8 is expressed as nine isoforms by alternative splicing with the molecular mass from 26 kDa to 62 kDa. Caspase 8 Monoclonal Antibody can recognize pro- and cleaved-caspase 8.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01885
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Caspase 8
Specificity Isoform 1, isoform 5 and isoform 7 are expressed in a wide variety of tissues. Highest expression in peripheral blood leukocytes, spleen, thymus and liver. Barely detectable in brain, testis and skeletal muscle.
Isotype IgG2b
Reacitivity Human,Mouse
Clone 98
Uniprot Q14790
Concentration None
Dilution WB 1:500-1:5000, IHC 1:100-1:400, IF 1:50-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names ALPS2B,Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein,Apoptotic cysteine protease,Apoptotic protease Mch-5,Apoptotic protease Mch5,CAP4,CASP-8,CASP8,CASP8,Caspase 8,Caspase 8 apoptosis related cysteine peptidase,Caspase-8 subunit p10,CED 3,FADD Like ICE,FADD-homologous ICE/CED-3-like protease,FADD-like ICE,FLICE,FLJ17672,ICE-like apoptotic protease 5,MACH alpha 1/2/3 protein,MACH,MACH beta 1/2/3/4 protein,MCH5,MGC78473,MORT1 associated ced 3 homolog,MORT1-associated CED-3 homolog,OTTHUMP00000163717,OTTHUMP00000163720,OTTHUMP00000163724,OTTHUMP00000163725,OTTHUMP00000165062,OTTHUMP00000165063,OTTHUMP00000165064,OTTHUMP00000206552,OTTHUMP00000206582
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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