Anti-Human/Mouse ACMSD Polyclonal Antibody

The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12885
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human ACMSD
Specificity
Isotype IgG
Reacitivity Human,Mouse
Clone
Uniprot Q8TDX5
Concentration 0.2 mg/mL
Dilution IHC 1:15-1:50
Formulation
Application IHC,ELISA
Other Names 2 amino 3 carboxymuconate 6 semialdehyde decarboxylase,2-amino-3-carboxymuconate-6-semialdehyde decarboxylase,acmsd,ACMSD,Aminocarboxymuconate semialdehyde decarboxylase,Picolinate carboxylase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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