Anti-Human LIMA1 Monoclonal Antibody

EPLIN is a cytoskeletal protein that is preferentially expressed in epithelial cells and is implicated in regulation of cytoskeletal dynamics and cytokinesis. In human,there are two known isoforms,EPLIN-a and -b,generated by alternative promoter usage from a single gene. EPLIN-a expression is often down-regulated in cancerous cells and tissues. This antibody recognizes both of isoforms of EPLN.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02290
Size 100μl
Host Type Mouse
Immunogen Fusion protein of EPLIN
Specificity Highly expressed in placenta, kidney, pancreas, prostate, ovary, spleen and heart. Also detected in lung, liver, brain, skeletal muscle, thymus, testis and intestine. Not detected in leukocytes. Isoform Beta expressed generally at very low levels. Isoform Alpha abundant in epithelial cells from mammary gland, prostate and in normal oral keratinocytes. Low levels in aortic endothelial cells and dermal fibroblasts. Not detectable in myocardium.
Isotype IgG1
Reacitivity Human
Clone 6578
Uniprot Q9UHB6
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names 1110021C24Rik,Epithelial protein lost in neoplasm,Epithelial protein lost in neoplasm beta,EPLIN,FLJ38853,LIM domain and actin binding 1,LIM domain and actin binding protein 1,LIM domain and actin-binding protein 1,LIMA1,LIMA1,MGC131726,SREBP3,Sterol regulatory element binding protein 3
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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