Anti-Human LBR Polyclonal Antibody

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. 
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Properties

Data Sheet Click for Datasheet
Catalog Number PA11943
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human LBR
Specificity
Isotype IgG
Reacitivity Human
Clone
Uniprot Q14739
Concentration 0.4 mg/mL
Dilution WB 1:500-1:2000, IHC 1:50-1:200
Formulation
Application WB,IHC,ELISA
Other Names DHCR 14B,DHCR14B,Integral nuclear envelope inner membrane protein,Lamin-B receptor,LBR,LBR,LMN 2R,LMN2R,MGC9041,PHA,PRO0650
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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