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Anti-Human ITGA3 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
ITGA3,also named as MSK18,CD49c,GAPB3 and FRP-2,belongs to the integrin alpha chain family. It is a receptor for fibronectin,laminin,collagen,epiligrin,thrombospondin and CSPG4. ITGA3 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. ITGA3 is highly concentrated in epithelial cells where it strongly adheres to Laminin-5 and Laminin-5 induced rapid adhesion can be blocked by antibodies against the alpha-3 integrin subunit. It can be cleaved into heavy chain(840aa) and light chain(176aa). This antibody can recognize the heavy chain.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02298
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Integrin alpha-3
Specificity Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
Isotype IgG2a
Reacitivity Human
Clone 1269
Uniprot P26006
Concentration None
Dilution WB 1:500-1:5000
Formulation
Application WB,IF,ELISA
Other Names AA407068,Antigen identified by monoclonal J143,CD49 antigen like family member C,CD49 antigen-like family member C,CD49c,CD49c antigen,FLJ34631,FLJ34704,FRP 2,FRP-2,FRP2,Galactoprotein B3,GAP B3,GAPB3,Integrin alpha 3,Integrin alpha-3 light chain,Integrin,alpha 3 (antigen CD49C,alpha 3 subunit of VLA-3 receptor),ITA3,ITGA 3,Itga3,MSK18,VCA 2,VCA2,Very late activation protein 3 receptor alpha 3 subunit,VL3A,VLA 3 alpha chain,VLA 3 subunit alpha,VLA-3 subunit alpha,VLA3a
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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