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Anti-Human GOLM1 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Golgi phosphoprotein 2 (GOLPH2,also known as GP73 or GOLM1) is a resident Golgi type-II membrane protein. It is predominantly expressed in the epithelial cells of many human tissues. GOLPH2 traffics through endosomes and can be secreted into the circulation. Its expression is upregulated in a number of tumors and GOLPH2 could be a promising serum marker for hepatocellular carcinoma.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02484
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of GP73/GOLPH2
Specificity Widely expressed. Highly expressed in colon, prostate, trachea and stomach. Expressed at lower level in testis, muscle, lymphoid tissues, white blood cells and spleen. Predominantly expressed by cells of the epithelial lineage. Expressed at low level in normal liver. Expression significantly increases in virus (HBV, HCV) infected liver. Expression does not increase in liver disease due to non-viral causes (alcohol-induced liver disease, autoimmune hepatitis). Increased expression in hepatocytes appears to be a general feature of advanced liver disease. In liver tissue from patients with adult giant-cell hepatitis (GCH), it is strongly expressed in hepatocyte-derived syncitial giant cells. Constitutively expressed by biliary epithelial cells but not by hepatocytes.
Isotype IgG1
Reacitivity Human
Clone 3D1F1
Uniprot Q8NBJ4
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names bA379P1.3,C9orf155,Chromosome 9 open reading frame 155,Golgi membrane protein 1,Golgi membrane protein GP73,Golgi phosphoprotein 2,Golgi protein 73 kD,Golgi protein 73kD,GOLM 1,GOLM1,GOLM1,GOLPH 2,GOLPH2,GP 73,GP73,PSEC0257
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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