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Anti-Human CK-20 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells. Keratin expression is highly regulated,tissue specific,and varies according to cell-state. Type I keratins consist of acidic,low molecular weight proteins with MW ranging from 40 kDa (KRT19) to 64 kDa (KRT9). Type 2 keratins consist of basic or neutral,high molecular weight proteins with MW from 52 kDa (KRT8) to 67 kDa (KRT18).Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01948
Size 100μl
Host Type Mouse
Immunogen Fusion protein of Cytokeratin 20
Specificity Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa.
Isotype IgG2b
Reacitivity Human
Clone 12
Uniprot P35900
Concentration None
Dilution WB 1:500-1:5000, IHC 1:20-1:200
Formulation
Application WB,IHC,ELISA
Other Names CD20,CK 20,CK-20,CK20,Cytokeratin-20,Cytokeratin20,K1C20,K20,KA20,Keratin 20,keratin 20,type I,keratin 21,rat,homolog of,Keratin,Keratin type I cytoskeletal 20,Keratin-20,Keratin20,KRT 20,KRT 21,KRT20,KRT21,MGC35423,OTTHUMP00000164518,Protein IT,type I cytoskeletal 20
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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