Anti-Human CD46 Polyclonal Antibody

The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization.
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Properties

Data Sheet Click for Datasheet
Catalog Number PA12394
Size 100μl
Host Type Rabbit
Immunogen Recombinant protein of human CD46
Specificity Expressed by all cells except erythrocytes.
Isotype IgG
Reacitivity Human
Clone
Uniprot P15529
Concentration 0.3 mg/mL
Dilution IHC 1:25-1:100
Formulation
Application IHC,ELISA
Other Names AHUS2,Antigen defined by monoclonal TRA 2 10,Antigen identified by monoclonal TRA 2 10,CD46,CD46 antigen,CD46 antigen complement regulatory protein,CD46 molecule,CD46 molecule complement regulatory protein,Complement membrane cofactor protein,MCP,MCP,Measles virus receptor,membrane cofactor protein (CD46,trophoblast-lymphocyte cross-reactive antigen),Membrane cofactor protein,MGC26544,MIC10,TLX,TRA2.10,Trophoblast leucocyte common antigen,Trophoblast leukocyte common antigen,Trophoblast lymphocyte cross reactive antigen
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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