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Anti-Human CD44 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration,tumor growth and progression. CD44 is also involved in lymphocyte activation,recirculation and homing,and in hematopoiesis. This protein exists in multiple isoforms (with molecular weight ranging from 16 kDa to over 200 kDa) generated by alternative RNA splicing and undergoes extensive post-translational modifications.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01906
Size 100μl
Host Type Mouse
Immunogen Fusion protein of CD44
Specificity Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas. Expression is repressed in neuroblastoma cells.
Isotype IgG2a
Reacitivity Human
Clone 23
Uniprot P16070
Concentration None
Dilution WB 1:500-1:5000, IHC 1:50-1:500, IF 1:10-1:100
Formulation
Application WB,IHC,IF,ELISA
Other Names LHR,BA-1,CD 44,CD44,CD44 antigen,CD44 molecule (Indian blood group),CD44 molecule,CD44,CDw44,Cell surface glycoprotein CD44,chondroitin sulfate proteoglycan 8,CSPG8,ECMR-III,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor,HCELL,hematopoietic cell E- and L-selectin ligand,Heparan sulfate proteoglycan,Hermes antigen,homing function and Indian blood group system,HSA,HUTCH-I,HUTCH1,Hyaluronate receptor,IN,INLU-related p80 Glycoprotein,MC56,MDU2,MDU3,MGC10468,MIC4,MUTCH1,PGP-1,PGP-I,PGP1,Phagocytic glycoprotein 1,Phagocytic glycoprotein I,Soluble CD44
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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