Anti-Human CASP9 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

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Data Sheet	Click for Datasheet
Catalog Number	MA01786
Size	100μl
Host Type	Mouse
Immunogen	Synthetic Peptide
Specificity	Ubiquitous, with highest expression in the heart, moderate expression in liver, skeletal muscle, and pancreas. Low levels in all other tissues. Within the heart, specifically expressed in myocytes.
Isotype	IgG
Reacitivity	Human
Clone	3I3
Uniprot	P55211
Concentration	1mg/mL
Dilution	WB 1:500-1:2000, IHC 1:50-300, IF 1:50-1:200, IP 1:100-1:300
Formulation
Application	WB,IHC-p,IF,IP
Other Names	APAF-3,APAF3,Apoptosis related cysteine peptidase,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,CASP9,Caspase 9 apoptosis related cysteine peptidase,Caspase 9 Dominant Negative,Caspase 9c,Caspase-9,Caspase-9 subunit p10,ICE LAP6,ICE like apoptotic protease 6,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,PPP1R56,protein phosphatase 1,regulatory subunit 56,RNCASP9
Storage	Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript	For research use only, not for use in diagnostic procedures.

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Anti-Human CASP9 Monoclonal Antibody

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