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Anti-Human C4A (gamma chain) Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
Complement C4,a component of the classical complement pathway,has an important role in innate immune function. C4 protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha,beta,and gamma chains (molecular wights 95,78,and 31 kDa) prior to secretion. The alpha chain is cleaved to release C4 anaphylatoxin,an antimicrobial peptide and a mediator of local inflammation. This antibody raised against 1543-1744aa of human C4A protein recognize C4 gamma chain.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01881
Size 100μl
Host Type Mouse
Immunogen Fusion protein of C4
Specificity Complement component C4 is expressed at highest levels in the liver, at moderate levels in the adrenal cortex, adrenal medulla, thyroid gland,and the kidney, and at lowest levels in the heart, ovary, small intestine, thymus, pancreas and spleen. The extra-hepatic sites of expression may be important for the local protection and inflammatory response.1 Publication
Isotype IgG1
Reacitivity Human
Clone 30
Uniprot P0C0L4
Concentration None
Dilution WB 1:2000-1:20000
Formulation
Application WB,ELISA
Other Names Acidic complement C4,Basic complement C4,CH,Chido blood group,Complement component 4A,Complement component 4B,RG,Rodgers blood group
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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