Anti-Human BID Monoclonal Antibody

BID,also named as p22 BID,can be cleaved into p11 BID,p13 BID and p15 BID. It is pro-apoptotic molecules. The major proteolytic product p15 BID allows the release of cytochrome c. BID-L,BID-EL and BID-ES induce ICE-like proteases and apoptosis. BID-S does not induce apoptosis. BID counters the protective effect of Bcl-2. .
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01876
Size 100μl
Host Type Mouse
Immunogen Fusion protein of BID
Specificity Isoform 2 and isoform 3 are expressed in spleen, bone marrow, cerebral and cerebellar cortex. Isoform 2 is expressed in spleen, pancreas and placenta (at protein level). Isoform 3 is expressed in lung, pancreas and spleen (at protein level). Isoform 4 is expressed in lung and pancreas (at protein level).
Isotype IgG1
Reacitivity Human
Clone 520
Uniprot P55957
Concentration None
Dilution WB 1:2000-1:20000, IHC 1:50-1:500, IF 1:20-1:200
Formulation
Application WB,IHC,IF,ELISA
Other Names Apoptic death agonist,Apoptotic death agonist BID,BH3 interacting domain death agonist,BH3 interacting domain death agonist p11,BH3 interacting domain death agonist p13,BH3 interacting domain death agonist p15,BH3-interacting domain death agonist p11,BID,BID isoform ES(1b),BID isoform L(2),BID isoform Si6,BID,Desmocollin type 4,FP497,Human BID coding sequence,MGC15319,MGC42355,p11 BID,p13 BID,p15 BID,p22 BID
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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