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Anti-Human ARHGDIB Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
ARHGDIB,also known as RhoGDI2,is a conserved member of the RhoGDI family and plays an important role in cell migrations. It regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them,and the subsequent binding of GTP to them. It is mainly in hematopoietic,endothelial,and epithelial cells. It has been linked to tumorigenesis and metastasis. RhoGDI2 expression is downregulated in several cancer types,such as bladder,lung and lymphoma,but is upregulated in prostate and gastric cancer.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01863
Size 100μl
Host Type Mouse
Immunogen Fusion protein of ARHGDIB
Specificity Detected in bone marrow, thymus and spleen.
Isotype IgG2b
Reacitivity Human
Clone
Uniprot P52566
Concentration None
Dilution WB 1:500-1:5000
Formulation
Application WB,ELISA
Other Names Arhgdib,D4,D4 GDP dissociation inhibitor,GDIA 2,GDIA2,GDID 4,GDID4,GDIR2,GDP dissociation inhibitor D4,LY GDI,Ly-GDI,LYGDI,MGC108926,RAP1GN1,Rho GDI 2,Rho GDI beta,Rho GDI2,Rho GDP dissociation inhibitor (GDI) beta,Rho GDP dissociation inhibitor 2,Rho GDP dissociation inhibitor beta,Rho GDP-dissociation inhibitor 2,Rho-GDI beta,RhoGDI2
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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