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Anti-Human ADRM1 Monoclonal Antibody

Categories: [ Antibodies][ Monoclonal Antibodies]
The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA02428
Size 100μl
Host Type Mouse
Immunogen Fusion Protein of ADRM1
Specificity
Isotype IgG3
Reacitivity Human
Clone 1A1A3
Uniprot Q16186
Concentration None
Dilution WB 1:5000-1:20000
Formulation
Application WB,ELISA
Other Names 110 kDa cell membrane glycoprotein,adhesion regulating molecule 1,Adhesion-regulating molecule 1,ADRM 1,Adrm1,ADRM1,ARM 1,ARM-1,ARM1,Gp110,hRpn13,M(r) 110,000 surface antigen,Proteasomal ubiquitin receptor ADRM1,proteasome regulatory particle non ATPase 13,Proteasome regulatory particle non-ATPase 13,Regulatory particle non ATPase 13,Rpn13,Rpn13 homolog
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.
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