ALK (mAb 16-39) Anti-Mouse Rat IgG MoAb

Anaplastic lymphoma kinase (ALK, anaplastic lymphoma kinase) is a receptor type tyrosine kinase, and is found to be expressed in the central and peripheral nervous system at late embryonic stage. Motegi et al. developed an agonist monoclonal antibody against the extracellular domain of ALK. This monoclonal antibody (clone mAb16-39) elicits tyrosine phosphorylation of ALK in human neuroblastoma (SK-N-SH) cells. And it also induces further phosphorylation of signal transfer molecules like IRD-1 (insulin receptor substrate-1) which interact with ALK. Moreover, continuous incubation with this antibody induced the cell-growth and neurite outgrowth of SK-N-SH cells (ref. 1).
List Price: $492
  • Buy 5 for $467.4 each and save 5%
  • Buy 21 for $442.8 each and save 10%
  • Buy 31 for $418.2 each and save 15%
  • Buy 51 for

Properties

Data Sheet Click for Datasheet
Catalog Number MA01039
Size 100 μg
Host Type Rat
Immunogen Recombinant protein of the extracellular domain of mouse ALK
Specificity
Isotype IgG2b
Reacitivity Mouse
Clone mAb 16-39
Uniprot
Concentration Please see datasheet.
Dilution
Formulation Lyophilized product from 1 % BSA in PBS containing 0.05 % NaN3
Application WB, immuno-precipitation, stimulation test.
Other Names Anaplastic Lymphoma Kinase;CD246; TFG/ALK; Ki1; Anaplastic Lymphoma Receptor Tyrosine Kinase
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

© Copyright 2024 TZYBIOTECH. All Rights Reserved. SiteMap