ALDH5A1 Antibody (Clone AT17F5)

This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD+-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter gamma-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene.
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Properties

Data Sheet Click for Datasheet
Catalog Number MA01032
Size 100 µL
Host Type Mouse
Immunogen Recombinant human ALDH5A1 (48-535aa) purified from E. coli
Specificity
Isotype Mouse IgG2a, k
Reacitivity Human
Clone Anti-human ALDH5A1 mAb, clone AT17F5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ALDH5A1 protein.
Uniprot
Concentration 1mg/ml
Dilution
Formulation Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Application ELISA, WB, Flow cytometry, ICC/IF
Other Names Succinate-semialdehyde dehydrogenase mitochondrial, SSADH, SSDH, Succinate-semialdehyde dehydrogenase, mitochondrial
Storage Lyophilized product: 5 years at 2 - 8°C; Solution: 2 years at -20°C.
Postscript For research use only, not for use in diagnostic procedures.

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