Recombinant Mouse Poliovirus Receptor-Related Protein 2 Protein

Categories: [Proteins / Peptides]
Nectin-2( CD112) is a member of the nectin family, which contains two Ig-like C2-type domains and one Ig-like V-type domain in the extracellular region. Nectins are type I transmembrane glycoproteins that are calcium-independent immunoglobulin (Ig)-like cell adhesion molecules (CAMs). Nectin2 is widely expressed in human tissues including brain, spinal cord, spleen, kidney, heart and liver. It can form trans-heterodimers with PVRL3/nectin-3 and interacts with CD226. Mutations of alleles of the murine CD112 gene can result in conditions such as morphologically aberrant spermatozoa. It may function in allergic reactions, and accordingly may used as a novel target for anti-allergic therapy.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP04633
Size 20ug,50ug,100ug…
Host Human Cells
Accession NP_033016.3
Molecular Weight 35.6 kDa
AP_Mol_Weight 40-45 kDa
Tag C-6His
Sequences Met 1-Gly 351
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names CD112;nectin2;Herpes virus entry mediator B;Herpesvirus entry mediator B;HveB;Murine herpes virus entry protein B;mHveB;Poliovirus receptor homolog;Poliovirus receptor-related protein 2;Pvrl2;
Bioactivity Measured by its binding ability in a functional ELISA.1. Immobilized mouse CD112-His at 10 µg/ml (100 μl/well) can bind biotinylated mouse DNAM1-His with a linear range of 0.156-5.0 µg/ml.2. Immobilized mouse CD112-His at 10 µg/ml (100 μl/well) can bind
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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