Recombinant Mouse Fibroblast Growth Factor 1/FGF-1/FGFa (Phe16-Asp155)Protein

Categories: [Proteins / Peptides]
FGF acidic is a 17 kDa nonglycosylated member of the FGF family of mitogenic peptides. FGF acidic, which is produced by multiple cell types, stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP04641
Size 20ug,50ug,100ug…
Host E.coli
Accession P61148
Molecular Weight 15.7 kDa
AP_Mol_Weight 16 kDa
Tag
Sequences Phe16-Asp155
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Fibroblast Growth Factor 1; FGF-1; Acidic Fibroblast Growth Factor; aFGF; Heparin-Binding Growth Factor 1; HBGF-1; Fgf1; Fgf-1; Fgfa
Bioactivity Measured by the dose-dependent stimulation of thymidine uptake by 3T3 cells in the presence of Heparin.The ED50 for this effect is less than 1.6 ng/mL.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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