Recombinant Human Retinol-Binding Protein 4 Protein

Categories: [Proteins / Peptides]
Retinol Binding Protein 4 (RBP4) is a member of the Lipocalin family and in the blood. RBP4 is the specific vector for retinol. RBP4 is expressed and secreted by adipose tissue, and is associated with insulin resistance. RBP4 delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin to prevents its loss by filtration through the kidney glomeruli. Defects in RBP4 cause retinol-binding protein deficiency and can cause night vision problems.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP04901
Size 20ug,50ug,100ug…
Host E.coli
Accession NP_006735.2
Molecular Weight 21.2 kDa
AP_Mol_Weight 20 kDa
Tag
Sequences Glu19-Leu201
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Retinol-Binding Protein 4; Plasma Retinol-Binding Protein; PRBP; RBP; RBP4
Bioactivity Measured by its ability to bind all-trans retinoic acid. The binding of retinoic acid results in the quenching of Trp fluorescence in RBP4.The 50% binding concentration (BC50) is > 1.0 ¦ÌM
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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