Recombinant Human Interferon alpha-4 Protein

Categories: [Proteins / Peptides]
Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow for communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors. They are typically divided among three IFN classes: Type I, Type II and Type III. IFNA4 is a secreted protein and produced by macrophages. Two variants of IFNA4 (IFNA4a and IFNA4b) are known, which differ from each other by changes in their coding regions at nucleotide positions 220 and 410 .
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05041
Size 20ug,50ug,100ug…
Host Human Cells
Accession P05014
Molecular Weight 20.4 kDa
AP_Mol_Weight 20 kDa
Tag C-6His
Sequences Cys24-Asp189
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Interferon alpha-4; Interferon alpha-4B; Interferon alpha-76;Interferon alpha-M1;IFNA4
Bioactivity Measured in antiviral assays using WISH cells infected with vesicular stomatitis virus.The ED50 for this effect is 2-10pg/mL.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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