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Recombinant Human Fibroblast Growth Factor 8/FGF-8F Protein (N-6His)

Categories: [Proteins / Peptides]
Fibroblast growth factor 8 (FGF-8) is a member of the fibroblast growth factor family. It is discovered as a growth factor essential for the androgen--dependent growth of mouse mammary carcinoma cells. Mouse FGF-8b shares 100% aa identity with human FGF-8b. FGF-8 is widely expressed during embryogenesis, and mediates epithelial--mesenchymal transitions. It plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. It is required for normal brain, eye, ear, limb development during embryogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05510
Size 20ug,50ug,100ug…
Host E.coli
Accession P55075-4
Molecular Weight 27.7 kDa
AP_Mol_Weight 30 kDa
Tag N-6His
Sequences Gln23-Arg244
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Fibroblast growth factor 8;Androgen-induced growth factor;Heparin-binding growth factor 8;AIGF;HBGF-8;FGF-8B
Bioactivity Measured in a cell proliferation assay using BALB/c 3T3 cells.The ED50 for this effect is less than 0.5 ug/ml.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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