Recombinant Human Complement Factor H-related 5/CFHR5 Protein(C-6His)

Categories: [Proteins / Peptides]
Complement factor H-related protein 5(FHR-5 for short), is a secreted protein which contains 9 Sushi (CCP/SCR) domains. It is expressed by the liver and secreted in plasma. The pattern of the deposits is similar to other complement components, suggesting that FHR-5 may play a role in complement activation and regulation. Defects in CFHR5 have been found in patients with atypical hemolytic uremic syndrome and may contribute to the disease. In contrast to typical hemolytic uremic syndrome, atypical forms have a poorer prognosis, with higher death rates and frequent progression to end-stage renal disease.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP05034
Size 20ug,50ug,100ug…
Host Human Cells
Accession Q9BXR6
Molecular Weight 63.5 kDa
AP_Mol_Weight 61 kDa
Tag C-6His
Sequences Glu19-Glu569
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Complement factor H-related protein 5;CFHR5;CFHL5;FHR5
Bioactivity
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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