Recombinant Human Cell Adhesion Molecule 3 Protein

Categories: [Proteins / Peptides]
Cell Adhesion Molecular Proteins are proteins located on the cell surface involved with the binding with other cells or with the extracellular matrix in the cell adhesion process. These proteins consists of three domains, an transmembrane domain, an intracellular domain that interacts with the cytoskeleton, and an extracellular domain that interacts with other CAMs of the same kind or with other CAMs or the extracellular matrix. Cell Adhesion Molecular 3 (CADM3) is a neural tissue-specific member of the nectin-like family of immunoglobulin superfamily. CADM3 interacts with EPB41L1 may regulate structure or function of cell-cell junctions. CADM3 has both calcium-independent homophilic cell-cell adhesion activity and calcium-independent heterophilic cell-cell adhesion activity with IGSF4, PVRL1 and PVRL3.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP04881
Size 20ug,50ug,100ug…
Host Human Cells
Accession NP_001120645.1
Molecular Weight 34.7 kDa
AP_Mol_Weight 40 kDa
Tag C-6His
Sequences Asn25-His330
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Cell Adhesion Molecule 3; Brain Immunoglobulin Receptor; Immunoglobulin Superfamily Member 4B; IgSF4B; Nectin-Like Protein 1; NECL-1; Synaptic Cell Adhesion Molecule 3; SynCAM3; TSLC1-Like Protein 1; TSLL1; CADM3; IGSF4B; NECL1; SYNCAM3; TSLL1
Bioactivity Measured by the ability of the immobilized protein to support the adhesion of C6 Rat brain glial cells. Human CADM3 immobilized (0.8 μg/ml, 100 μl/well) will mediate >30% C6 cell adhesion.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.

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