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Recombinant Human CD200 Receptor 1 Protein

Categories: [Proteins / Peptides]
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal.
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Properties

Data Sheet Click for Datasheet
Catalog Number TP04880
Size 20ug,50ug,100ug…
Host Human Cells
Accession AAI43394.1
Molecular Weight 25.2 kDa
AP_Mol_Weight 58 kDa
Tag C-6His
Sequences Ala27-Leu266
Purity > 95% by HPLC
Concentration
Formulation PBS
Other Names Cell Surface Glycoprotein CD200 Receptor 1; CD200 Cell Surface Glycoprotein Receptor; Cell Surface Glycoprotein OX2 Receptor 1; CD200R1; CD200R; CRTR2; MOX2R; OX2R
Bioactivity Measured by its binding ability in a functional ELISA. Immobilized human CD200R1 at 1 μg/ml (100 μl/well) can bind human CD200 with a linear range of 0.12-16 ng/ml.
Storage Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Postscript For research use only, not for use in diagnostic procedures.
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